PDE1A inhibition elicits cGMP-dependent relaxation of rat mesenteric arteries
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چکیده
منابع مشابه
Cyclooxygenase-2 Inhibition Restored Endothelium-Mediated Relaxation in Old Obese Zucker Rat Mesenteric Arteries
Metabolic syndrome is associated with reduced endothelial vasodilator function. It is also associated with the induction of cyclooxygenase-2 (COX2), which produces vasoactive prostanoids. The frequency of metabolic syndrome increases with age and aging per se is a risk factor associated with reduced endothelium-mediated relaxation. Nevertheless, the combined effect of aging and metabolic syndro...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 2017
ISSN: 0007-1188
DOI: 10.1111/bph.14034